Mary & May’s Spicule Retinol PDRN Cream is an advanced anti-aging moisturizer designed to smooth wrinkles, refine pores, and improve overall skin texture. Combining powerful actives like nano-liposomal retinol and centella-derived PDRN, the formula helps stimulate skin renewal and support collagen production, promoting firmer, smoother, and more youthful-looking skin.

The cream contains 2,000 ppm of marine-derived micro-spicules that are smaller than pores, allowing them to create temporary micro-pathways in the skin. These microscopic spicules help enhance the absorption of active ingredients, enabling retinol and PDRN to penetrate deeper into the skin for more effective results in reducing the appearance of fine lines, enlarged pores, and uneven texture.

Nano liposome retinol is used in the formula to improve stability and minimize irritation often associated with traditional retinol. Encapsulating retinol in liposomes helps deliver the ingredient gradually into the skin, making it more comfortable and suitable for regular use while still providing visible anti-aging benefits.

The addition of CICA PDRN helps support skin regeneration and repair by targeting weakened or damaged skin cells. Derived from centella asiatica, this ingredient also helps soothe irritation while reinforcing the skin’s collagen barrier, leaving the complexion healthier and more resilient.

To ensure the skin remains balanced and hydrated, the formula includes the Safe 4X soothing complex featuring panthenol, ceramide NP, hyaluronic acid, and allantoin. These barrier-supporting ingredients help calm the skin, maintain moisture, and reduce the potential irritation that can occur with retinol-based treatments.